Analyzing VBI Vaccines (VBIV) and Trillium Therapeutics (TRIL)

VBI Vaccines (NASDAQ: VBIV) and Trillium Therapeutics (NASDAQ:TRIL) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, valuation, dividends, profitability, institutional ownership, risk and analyst recommendations.

Analyst Recommendations

This is a summary of recent ratings and recommmendations for VBI Vaccines and Trillium Therapeutics, as provided by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
VBI Vaccines 0 0 2 0 3.00
Trillium Therapeutics 0 0 3 0 3.00

VBI Vaccines currently has a consensus price target of $10.00, indicating a potential upside of 139.81%. Trillium Therapeutics has a consensus price target of $12.50, indicating a potential upside of 31.58%. Given VBI Vaccines’ higher probable upside, analysts clearly believe VBI Vaccines is more favorable than Trillium Therapeutics.


This table compares VBI Vaccines and Trillium Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
VBI Vaccines N/A N/A N/A
Trillium Therapeutics N/A -223.93% -68.01%

Valuation & Earnings

This table compares VBI Vaccines and Trillium Therapeutics’ top-line revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio NetIncome Earnings Per Share Price/Earnings Ratio
VBI Vaccines $550,000.00 483.80 -$23.20 million N/A N/A
Trillium Therapeutics N/A N/A -$23.96 million ($3.79) -2.51

VBI Vaccines has higher revenue and earnings than Trillium Therapeutics.

Volatility & Risk

VBI Vaccines has a beta of 2.32, suggesting that its stock price is 132% more volatile than the S&P 500. Comparatively, Trillium Therapeutics has a beta of 1.53, suggesting that its stock price is 53% more volatile than the S&P 500.

Insider & Institutional Ownership

20.4% of VBI Vaccines shares are held by institutional investors. Comparatively, 48.0% of Trillium Therapeutics shares are held by institutional investors. 34.1% of VBI Vaccines shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.


VBI Vaccines beats Trillium Therapeutics on 7 of the 9 factors compared between the two stocks.

VBI Vaccines Company Profile

VBI Vaccines Inc., formerly SciVac Therapeutics Inc., is a biotechnology company. The Company is engaged in developing various technologies that focus on vaccine protection. It has developed an enveloped virus like particle (eVLP) vaccine platform that allows for the design of enveloped VLP vaccines. It is involved in various projects related to human cytomegalovirus (CMV) and other antigens. It is engaged in developing an experimental CMV vaccine using its eVLP vaccine platform. The vaccine is based on the CMV glycoprotein B antigen and is adjuvanted with aluminum phosphate. The eVLP vaccine technology allows for the expression of envelope glyco-proteins within a lipid-bilayer membrane of a VLP. It is developing a therapeutic vaccine candidate for glioblastoma multiforme (GBM). It is developing a vaccine to prevent respiratory syncytial virus (RSV) infection. It also offers Sci-B-Vac, which is a third-generation hepatitis B vaccine.

Trillium Therapeutics Company Profile

Trillium Therapeutics Inc., a clinical-stage immuno-oncology company, develops therapies for the treatment of cancer. The company’s lead program is TTI-621, a SIRPaFc fusion protein that acts a soluble decoy receptor preventing CD47 from delivering its inhibitory signal, which is in Phase I clinical trial for advanced hematologic malignancies and solid tumors therapy. Its product candidates also include TTI-622, an IgG4 SIRPaFc protein for combination therapy; bromodomain inhibitor; and epidermal growth factor receptor antagonist, which are in preclinical development stage, as well as undisclosed immuno-oncology targets that are in the discovery Phase. The company was formerly known as Stem Cell Therapeutics Corp. and changed its name to Trillium Therapeutics Inc. in June 2014. Trillium Therapeutics Inc. was founded in 2004 and is headquartered in Mississauga, Canada.

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