Head to Head Survey: Natera (NASDAQ:NTRA) & Personalis (NASDAQ:PSNL)

Natera (NASDAQ:NTRA) and Personalis (NASDAQ:PSNL) are both medical companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, valuation, institutional ownership, analyst recommendations, earnings, risk and profitability.

Analyst Recommendations

This is a breakdown of current ratings and recommmendations for Natera and Personalis, as provided by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Natera 0 2 3 0 2.60
Personalis 0 0 5 0 3.00

Natera presently has a consensus price target of $42.40, suggesting a potential upside of 15.47%. Personalis has a consensus price target of $26.25, suggesting a potential upside of 179.26%. Given Personalis’ stronger consensus rating and higher possible upside, analysts clearly believe Personalis is more favorable than Natera.


This table compares Natera and Personalis’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Natera -42.45% -252.79% -42.01%
Personalis N/A N/A N/A

Insider & Institutional Ownership

84.9% of Natera shares are held by institutional investors. Comparatively, 50.5% of Personalis shares are held by institutional investors. 9.3% of Natera shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Earnings & Valuation

This table compares Natera and Personalis’ top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Natera $257.65 million 11.05 -$128.15 million ($2.15) -17.08
Personalis N/A N/A N/A N/A N/A

Personalis has lower revenue, but higher earnings than Natera.


Personalis beats Natera on 6 of the 9 factors compared between the two stocks.

About Natera

Natera, Inc., a diagnostics company, provides preconception and prenatal genetic testing services. It primarily offers Panorama, a non-invasive prenatal test that screens for chromosomal abnormalities of a fetus with a blood draw from the mother; Vistara, a single-gene mutations screening test to identify single-gene disorder; Horizon carrier screening to determine carrier status for various genetic diseases that could be passed on to the carrier's children; and Spectrum pre-implantation genetic screening and Spectrum pre-implantation genetic diagnosis to analyze chromosomal anomalies or inherited genetic conditions during an in vitro fertilization cycle. The company also provides Anora products of conception test to analyze fetal chromosomes to understand the cause of miscarriage; and non-invasive paternity testing products to determine paternity by analyzing the fragments of fetal deoxyribonucleic acid in a pregnant mother's blood and a blood sample from the alleged father. In addition, it offers Constellation, a cloud-based software product that allows laboratory customers to gain access through the cloud to the company's algorithms and bioinformatics in order to validate and launch tests; Evercord, a cord blood and cord tissue processing and storage service; and Signatera, a circulating tumor DNA technology that analyzes and tracks mutations to an individual's tumor. The company offers products through its direct sales force, as well as through a network of approximately 100 laboratory and distribution partners in the United States and internationally. Natera, Inc. has research collaborations with the Institut Jules Bordet and Fox Chase Cancer Center. The company was formerly known as Gene Security Network, Inc. and changed its name to Natera, Inc. in 2012. Natera, Inc. was founded in 2003 and is headquartered in San Carlos, California.

About Personalis

Personalis, Inc. operates as a cancer genomics company worldwide. The company provides sequencing and data analysis services to support the development of cancer therapies. It offers NeXT Platform, which provides data for cancer therapy development, personalized therapies, therapy selection, and diagnostics. The company also provides a complementary liquid biopsy assay that analyzes various human genes versus. It serves approximately 45 biopharmaceutical customers, including a range of pharmaceutical companies. The company was founded in 2011 and is headquartered in Menlo Park, California.

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