GRI Bio (NASDAQ:GRI – Get Free Report) and Immuneering (NASDAQ:IMRX – Get Free Report) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, valuation, dividends, profitability, analyst recommendations, institutional ownership and risk.
Valuation and Earnings
This table compares GRI Bio and Immuneering”s gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| GRI Bio | N/A | N/A | -$8.21 million | ($8.39) | -0.40 |
| Immuneering | N/A | N/A | -$61.04 million | ($1.78) | -2.74 |
Risk & Volatility
GRI Bio has a beta of -1.39, meaning that its stock price is 239% less volatile than the S&P 500. Comparatively, Immuneering has a beta of 0.48, meaning that its stock price is 52% less volatile than the S&P 500.
Institutional & Insider Ownership
34.0% of GRI Bio shares are held by institutional investors. Comparatively, 67.7% of Immuneering shares are held by institutional investors. 8.7% of GRI Bio shares are held by insiders. Comparatively, 22.9% of Immuneering shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.
Analyst Ratings
This is a summary of current ratings and price targets for GRI Bio and Immuneering, as reported by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| GRI Bio | 1 | 0 | 2 | 0 | 2.33 |
| Immuneering | 1 | 0 | 5 | 1 | 2.86 |
GRI Bio currently has a consensus target price of $644.00, suggesting a potential upside of 19,297.59%. Immuneering has a consensus target price of $16.50, suggesting a potential upside of 238.81%. Given GRI Bio’s higher possible upside, equities analysts plainly believe GRI Bio is more favorable than Immuneering.
Profitability
This table compares GRI Bio and Immuneering’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| GRI Bio | N/A | -426.23% | -222.24% |
| Immuneering | N/A | -73.49% | -65.01% |
Summary
Immuneering beats GRI Bio on 9 of the 12 factors compared between the two stocks.
About GRI Bio
GRI Bio, Inc., a clinical-stage biopharmaceutical company, focuses on treating inflammatory, fibrotic, and autoimmune diseases in the United States. Its product pipeline comprises GRI-0621, which is in phase II clinical development for the treatment of idiopathic pulmonary fibrosis; GRI-0803 which is in phase I trial for the treatment of systematic lupus erythematosus; GRI-0124, which is in pre-clinical development for the treatment of primary sclerosing cholangitis; and GRI-0729 in pre-clinical development. The company also develops ADAIR and ADMIR for treatment of attention -deficit/hyperactivity disorder. GRI Bio, Inc. was formerly known as Glycoregimmune, Inc. GRI Bio, Inc. was founded in 2009 and is based in LA Jolla, California.
About Immuneering
Immuneering Corporation, a clinical-stage oncology company, engages in the development of medicines for broad populations of cancer patients. Its lead product candidates include IMM-1-104, a dual-MEK inhibitor currently under Phase 1/2a clinical trial to treat patients with cancer, including pancreatic, melanoma, colorectal, and non-small cell lung cancer caused by mutations of RAS and/or RAF; and IMM-6-415 is in Investigational New Drug application to treat solid tumors. Immuneering Corporation was incorporated in 2008 and is based in Cambridge, Massachusetts.
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