Kalaris Therapeutics (NASDAQ:KLRS – Get Free Report) and Ascendis Pharma A/S (NASDAQ:ASND – Get Free Report) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their valuation, analyst recommendations, earnings, dividends, profitability, risk and institutional ownership.
Volatility and Risk
Kalaris Therapeutics has a beta of 0.18, indicating that its share price is 82% less volatile than the S&P 500. Comparatively, Ascendis Pharma A/S has a beta of 0.49, indicating that its share price is 51% less volatile than the S&P 500.
Profitability
This table compares Kalaris Therapeutics and Ascendis Pharma A/S’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Kalaris Therapeutics | N/A | -73.11% | -43.56% |
| Ascendis Pharma A/S | -30.85% | N/A | -19.63% |
Analyst Recommendations
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Kalaris Therapeutics | 1 | 1 | 4 | 1 | 2.71 |
| Ascendis Pharma A/S | 1 | 0 | 17 | 1 | 2.95 |
Kalaris Therapeutics presently has a consensus target price of $14.00, suggesting a potential upside of 122.93%. Ascendis Pharma A/S has a consensus target price of $291.56, suggesting a potential upside of 21.33%. Given Kalaris Therapeutics’ higher possible upside, research analysts clearly believe Kalaris Therapeutics is more favorable than Ascendis Pharma A/S.
Earnings and Valuation
This table compares Kalaris Therapeutics and Ascendis Pharma A/S”s top-line revenue, earnings per share and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Kalaris Therapeutics | N/A | N/A | -$43.44 million | ($4.21) | -1.49 |
| Ascendis Pharma A/S | $814.57 million | 18.40 | -$258.00 million | ($4.40) | -54.61 |
Kalaris Therapeutics has higher earnings, but lower revenue than Ascendis Pharma A/S. Ascendis Pharma A/S is trading at a lower price-to-earnings ratio than Kalaris Therapeutics, indicating that it is currently the more affordable of the two stocks.
Insider & Institutional Ownership
66.1% of Kalaris Therapeutics shares are owned by institutional investors. 75.0% of Kalaris Therapeutics shares are owned by insiders. Comparatively, 40.0% of Ascendis Pharma A/S shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.
Summary
Kalaris Therapeutics beats Ascendis Pharma A/S on 7 of the 13 factors compared between the two stocks.
About Kalaris Therapeutics
Allovir, Inc., a clinical-stage cell therapy company, engages in the research and development of allogeneic, off-the-shelf multi-virus specific T cell (VST) therapies to prevent and treat devastating viral-associated diseases. The company’s lead product is posoleucel, an allogeneic, off-the-shelf VST therapy, to treat BK virus, cytomegalovirus, adenovirus, Epstein-Barr virus, human herpesvirus 6, and JC virus. Its preclinical and clinical development product candidates include ALVR106 for the respiratory syncytial virus, influenza, parainfluenza virus, and human metapneumovirus; ALVR109 to treat SARS-CoV-2 and COVID-19; ALVR107 for treating hepatitis B; and ALVR108. The company was formerly known as ViraCyte, Inc. and changed its name to Allovir, Inc. in May 2019. Allovir, Inc. was founded in 2013 and is based in Waltham, Massachusetts.
About Ascendis Pharma A/S
Ascendis Pharma A/S, a biopharmaceutical company, focuses on developing therapies for unmet medical needs. It offers SKYTROFA for treating patients with growth hormone deficiency (GHD). The company is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is headquartered in Hellerup, Denmark.
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